Synthe'Ses and Reactions of β-Chlorovinyl Sulfones

Cycloaddition reactions of unsaturated sulfones

The reaction of a series of allyl-substituted bis(phenylsulfony1)methanes or dimethyl malonates with 2,3-bis(phenylsulfonyl)l13-butadiene in the presence of base afforded alkenyl-substituted allenes in good yield. The reaction proceeds by initial attack of the soft carbanion onto the terminal position of the diene and subsequent PhS02elimination to give the phenylsulfonyl substituted allene. Th...

Catalytic asymmetric conjugate boration of α,β-unsaturated sulfones.

The α,β-unsaturated sulfones are suitable activated olefins in catalytic asymmetric conjugate β-boration. These substrates undergo smooth conjugate addition of bis(pinacolato)diboron [B(2)(pin)(2)] catalyzed by nonracemic Cu(I)-diphosphine complexes to provide, upon subsequent oxidation, β-hydroxy sulfones in good yields and high enantiocontrol.

Catalytic enantioselective Strecker reactions and analogous syntheses.

3.1. Overview 2807 3.2. Chiral Aluminum(III) Complexes as a Catalyst 2808 3.2.1. Aluminum(III)-Salen-Based Catalysts 2808 3.2.2. Aluminum(III)-Binaphthol-Based Catalysts 2810 3.3. Chiral Titanium(IV) Complexes as a Catalyst 2814 3.3.1. Titanium(IV)-Peptide-Based Catalysts 2814 3.3.2. Titanium(IV)-Diol-Based Catalysts 2817 3.4. Chiral Zirconium(IV) Complexes as a Catalyst 2818 3.4.1. The Catalyt...

SYNTHESES AND REACTIONS OF PYRAZINE AND QUINOXALINE 1.1 Pyrazine

Dialkylboron guanidinates: syntheses, structures and carbodiimide de-insertion reactions.

The synthesis of novel dialkylboron guanidinates is reported: the symmetrical compounds, (Me2N)C(NR)2BR'2 [R = iPr, R' = Nrb (1); R = Cy, R' = Nrb (2); R = iPr, R' = Cy (3); R = R' = Cy (4); R = 2,6-iPr2-C6H3; R' = Cy (5); Nrb = exo-2-norbornyl] and the asymmetrically coordinated {iPr(H)N}C(NiPr)(NAr)BCy2 [Ar = Ph (6), 4-Me-C6H4 (7), 4-tBu-C6H4 (8)] were prepared by the salt metathesis method f...